Roybal Centers for Translational Research on Dementia Care Provider Support (P30 - Clinical Trial Required) | RFA AG 19 007

Opportunity Information: Apply for RFA AG 19 007

The Roybal Centers for Translational Research on Dementia Care Provider Support (P30 - Clinical Trial Required) funding opportunity (RFA-AG-19-007) is a National Institutes of Health (NIH) center grant designed to build and support Edward R. Roybal Centers focused on developing and testing behavioral interventions that strengthen dementia care provider support for Alzheimers disease and Alzheimers disease related dementias (AD/ADRD). The central aim is not basic discovery alone, but practical, real-world intervention development that can improve the health, well-being, and functional capacity of the people and systems responsible for caring for individuals living with dementia. In plain terms, the program is meant to help move promising caregiving support ideas into stronger, more usable interventions that can be implemented in clinics, communities, long-term care settings, and other caregiving environments.

A defining feature of this FOA is its emphasis on translational intervention development research across the NIH Stage Model, specifically supporting pilot studies from Stage 0 through Stage IV. That means centers are expected to support the full early-to-later pipeline: from foundational work that clarifies the intervention targets and principles (Stage 0), through intervention creation and refinement (Stages I and II), to efficacy testing under more controlled conditions (Stage III), and ultimately to effectiveness, implementation, and scalability testing in real-world settings (Stage IV). The FOA frames this as a multidirectional process, recognizing that intervention development rarely proceeds in a straight line; findings from pilot tests and real-world implementation challenges are expected to feed back into redesign and optimization so that the end products are both potent (meaningfully impactful) and implementable (practical, sustainable, and adoptable by the settings that need them).

Because the FOA specifies "Clinical Trial Required," applicants should plan for research that includes clinical trial activity as part of the center-supported projects. In the context of behavioral intervention development for caregiver support, this often involves structured testing of intervention components, delivery approaches, or service models, with defined outcomes and prospective evaluation. The intent is to ensure that centers are not only proposing supportive programs in concept, but are also rigorously evaluating them through pilot and trial methods aligned with the stage of development.

The opportunity uses the P30 funding mechanism, which is typically used to support shared infrastructure, cores, and an organized research program rather than a single stand-alone project. In practice, a Roybal Center award generally supports a coordinated environment that can generate, refine, and test multiple intervention projects, often with shared resources such as scientific leadership, methods support, participant recruitment resources, data management, community or health system partnerships, and dissemination or implementation expertise. The FOA highlights "principle-driven" behavioral interventions, signaling that the center should be grounded in clear behavioral theory or intervention principles and should demonstrate how the underlying mechanisms and design choices link to caregiver and system outcomes.

Eligibility is broad and includes many types of U.S.-based organizations: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; and Native American tribal organizations that are not federally recognized. It also includes public housing authorities/Indian housing authorities, nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education when specified in the listing), for-profit organizations (other than small businesses), and small businesses. The FOA also explicitly calls out a range of additional eligible applicants, including Hispanic-serving institutions, historically Black colleges and universities (HBCUs), tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and Asian American Native American Pacific Islander serving institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.

On the international participation side, non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as applicant organizations. However, non-domestic components of U.S. organizations are eligible, and foreign components, as defined by the NIH Grants Policy Statement, are allowed. This setup typically supports situations where a U.S.-based applicant leads the center while including justified international collaborations or activities that meaningfully contribute to the research aims.

Administrative details from the source information include that the opportunity is categorized as a discretionary grant in the health funding activity category, with CFDA number 93.866. The NIH is the sponsoring agency. The posting lists an award ceiling of $500,000, with an original closing date of October 18, 2018, and a creation date of June 7, 2018. Overall, the grant is aimed at creating sustained, center-based capacity to produce tested and scalable caregiver-support interventions for AD/ADRD, moving beyond promising ideas into interventions that can be delivered effectively in the settings where caregivers and care systems actually operate.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Roybal Centers for Translational Research on Dementia Care Provider Support (P30 - Clinical Trial Required)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
• This funding opportunity was created on 2018-06-07.
• Applicants must submit their applications by 2018-10-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $500,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA AG 19 007

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