Opportunity Information: Apply for HRSA 25 059
The Health Resources and Services Administration (HRSA) is offering a cooperative agreement opportunity titled Improving Mental Health and Engagement in Care Among People with HIV - Evaluation Provider (EP), Funding Opportunity Number HRSA-25-059 (CFDA 93.928). This is a discretionary health funding opportunity under the Ryan White HIV/AIDS Program (RWHAP) Special Projects of National Significance (SPNS) portfolio. HRSA expects to make one award for an organization that will serve as the national Evaluation Provider, working alongside a separately funded Implementation Technical Assistance Provider (ITAP) under a companion notice of funding opportunity. The EP and ITAP are required to co-lead the overall initiative, meaning the evaluation function is not a side activity but a central leadership role that shapes how sites implement, learn, and improve over time. Applications were originally due March 18, 2025.
The initiative is centered on improving outcomes for people with HIV who also have mental health conditions and who are out of care or struggling with retention in care. The core idea is to support a national cohort of implementation sites as they adapt and put into practice culturally responsive interventions that better engage people in both HIV primary care and mental health services. While the initiative is anchored in this population, the EP and ITAP can also identify additional priority populations when selecting implementation sites, including populations highlighted in the National HIV/AIDS Strategy. The broader purpose is to generate practical, transferable learning about what strategies actually work across different settings and communities to improve engagement in care, mental health outcomes, and HIV outcomes.
HRSA lays out three main objectives for this initiative. Objective 1 focuses on implementation support: helping a cohort of sites adapt and implement culturally responsive interventions designed to engage and retain people with co-occurring HIV and mental health needs in appropriate care. Objective 2 is the evaluation mission, which is where the EP has primary responsibility. The EP must evaluate how the interventions are implemented using implementation science frameworks, and continuously document and share findings throughout the project to support real-time learning rather than only end-of-project reporting. The evaluation is expected to look at how interventions are adapted in practice, what barriers and facilitators affect implementation, what implementation strategies are used to make the work succeed, what the costs are, and what outcomes are observed across implementation measures as well as client and service outcomes. Objective 3 is about scaling learning beyond the funded sites by creating and disseminating user-friendly multimedia products that other RWHAP organizations can use to replicate effective interventions in their own settings, making the deliverables practical and accessible rather than purely technical reports.
Eligible applicants are domestic organizations only, not individuals. HRSA defines domestic broadly to include the 50 states, Washington, DC, Puerto Rico, and several US territories and freely associated states, including the Northern Mariana Islands, American Samoa, Guam, the US Virgin Islands, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau. Eligible organization types include public and nonprofit private entities such as state and local governments, academic institutions (including private institutions of higher education), local health departments, nonprofit hospitals and outpatient clinics, community health centers supported under Section 330 of the Public Health Service Act, faith-based and community-based organizations, and Indian Tribes or Tribal organizations with or without federal recognition. The EligibleApplicants list also includes nonprofits with and without 501(c)(3) status, and Native American tribal organizations (other than federally recognized tribal governments).
In practical terms, this opportunity is looking for an organization with strong national evaluation capacity and deep familiarity with implementation science to guide an initiative that blends service innovation with rigorous, usable learning. The EP is expected to help the RWHAP field understand not just whether engagement and mental health interventions work, but how they can be adapted, implemented, afforded, and sustained across real-world HIV care settings serving diverse priority populations.Apply for HRSA 25 059
- The Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Improving Mental Health and Engagement in Care Among People with HIV — Evaluation Provider" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.928.
- This funding opportunity was created on 2025-01-16.
- Applicants must submit their applications by 2025-03-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
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Frequently Asked Questions (FAQs)
What is the name of this funding opportunity?
The opportunity is titled Improving Mental Health and Engagement in Care Among People with HIV - Evaluation Provider (EP).
What agency is offering this opportunity?
The opportunity is offered by the Health Resources and Services Administration (HRSA).
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is HRSA-25-059.
What is the CFDA number associated with this opportunity?
The CFDA number listed is 93.928.
What type of award is this?
This is a cooperative agreement and is described as a discretionary health funding opportunity.
Which HRSA program and portfolio does this fall under?
This opportunity is under the Ryan White HIV/AIDS Program (RWHAP), within the Special Projects of National Significance (SPNS) portfolio.
How many awards does HRSA expect to make?
HRSA expects to make one award for an organization to serve as the national Evaluation Provider (EP).
What is the role of the Evaluation Provider (EP)?
The EP serves as the national Evaluation Provider for the initiative. The EP has primary responsibility for the evaluation mission, including evaluating how interventions are implemented using implementation science frameworks and continuously documenting and sharing findings throughout the project to support real-time learning.
Is there another national partner funded under a separate notice?
Yes. The EP will work alongside a separately funded Implementation Technical Assistance Provider (ITAP) under a companion notice of funding opportunity.
Do the EP and ITAP have to work together in a specific way?
Yes. The EP and ITAP are required to co-lead the overall initiative. The evaluation function is described as a central leadership role that helps shape how sites implement, learn, and improve over time.
When were applications originally due?
Applications were originally due March 18, 2025.
What is the main focus of the initiative?
The initiative centers on improving outcomes for people with HIV who also have mental health conditions, particularly those who are out of care or struggling with retention in care.
What is the core approach the initiative plans to use?
The initiative aims to support a national cohort of implementation sites as they adapt and implement culturally responsive interventions that better engage people in both HIV primary care and mental health services.
Can the initiative focus on additional priority populations beyond the core population described?
Yes. While anchored in people with HIV and mental health conditions who are out of care or poorly retained, the EP and ITAP can identify additional priority populations when selecting implementation sites, including populations highlighted in the National HIV/AIDS Strategy.
What is the broader purpose of this initiative beyond the funded sites?
The broader purpose is to generate practical, transferable learning about which strategies work across different settings and communities to improve engagement in care, mental health outcomes, and HIV outcomes.
What are the three main objectives described for this initiative?
HRSA describes three objectives: (1) implementation support for a cohort of sites to adapt and implement culturally responsive interventions; (2) a robust evaluation mission led by the EP using implementation science approaches with continuous sharing of findings; and (3) scaling and dissemination through user-friendly multimedia products that support replication across RWHAP organizations.
What does Objective 1 focus on?
Objective 1 focuses on implementation support, helping a cohort of sites adapt and implement culturally responsive interventions designed to engage and retain people with co-occurring HIV and mental health needs in appropriate care.
What does Objective 2 require from the Evaluation Provider?
Objective 2 is the evaluation mission where the EP has primary responsibility. The EP must evaluate implementation using implementation science frameworks and continuously document and share findings during the project to support real-time learning, not only end-of-project reporting.
What specific evaluation topics or questions are expected to be addressed?
The evaluation is expected to examine: how interventions are adapted in practice; barriers and facilitators affecting implementation; implementation strategies used to make the work succeed; costs; and outcomes across implementation measures as well as client and service outcomes.
What does Objective 3 emphasize?
Objective 3 emphasizes scaling learning beyond the funded sites by creating and disseminating user-friendly multimedia products that other RWHAP organizations can use to replicate effective interventions in their own settings. The deliverables are intended to be practical and accessible, not just technical reports.
Who is eligible to apply?
Eligible applicants are domestic organizations only. Individuals are not eligible.
What does HRSA mean by "domestic" for eligibility purposes?
HRSA defines domestic to include the 50 states, Washington, DC, Puerto Rico, and multiple U.S. territories and freely associated states, including the Northern Mariana Islands, American Samoa, Guam, the U.S. Virgin Islands, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau.
What types of organizations are listed as eligible?
Eligible organization types include public and nonprofit private entities such as: state and local governments; academic institutions (including private institutions of higher education); local health departments; nonprofit hospitals and outpatient clinics; community health centers supported under Section 330 of the Public Health Service Act; faith-based and community-based organizations; and Indian Tribes or Tribal organizations with or without federal recognition.
Are nonprofits without 501(c)(3) status eligible?
Yes. The EligibleApplicants list includes nonprofits with and without 501(c)(3) status.
Are Tribal organizations eligible even if they are not federally recognized?
Yes. Eligibility includes Indian Tribes or Tribal organizations with or without federal recognition, and it also lists Native American tribal organizations (other than federally recognized tribal governments).
What kind of capacity is HRSA looking for in an Evaluation Provider?
The opportunity is seeking an organization with strong national evaluation capacity and deep familiarity with implementation science to guide an initiative that blends service innovation with rigorous, usable learning.
What is the EP ultimately expected to help the RWHAP field understand?
The EP is expected to help the RWHAP field understand not just whether engagement and mental health interventions work, but how they can be adapted, implemented, afforded, and sustained across real-world HIV care settings serving diverse priority populations.
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| Ryan White HIV/AIDS Program (RWHAP) Web-Based Platform for HIV Tools and Resources Apply for HRSA 25 062 Funding Number: HRSA 25 062 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Street Medicine Interventions for People with HIV who are Unsheltered - Demonstration Sites Apply for HRSA 25 056 Funding Number: HRSA 25 056 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Street Medicine Interventions for People with HIV who are Unsheltered – Capacity Builder Provider (HRSA-25-055) and Street Medicine Interventions for People with HIV who are Unsheltered – Evaluation Provider (HRSA-25-057) Apply for HRSA 25 055 Funding Number: HRSA 25 055 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Improving Mental Health and Engagement in Care Among People with HIV — Implementation Technical Assistance Provider Apply for HRSA 25 058 Funding Number: HRSA 25 058 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Street Medicine Interventions for People with HIV who are Unsheltered – Capacity Builder Provider (HRSA-25-055) and Street Medicine Interventions for People with HIV who are Unsheltered – Evaluation Provider (HRSA-25-057) Apply for HRSA 25 057 Funding Number: HRSA 25 057 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
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| Behavioral Health Workforce Education and Training Program for Paraprofessionals Apply for HRSA 25 066 Funding Number: HRSA 25 066 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| Telehealth Research Center Apply for HRSA 25 045 Funding Number: HRSA 25 045 Agency: Health Resources and Services Administration Category: Health Funding Amount: $950,000 |
| Regional Telehealth Resource Centers Apply for HRSA 25 042 Funding Number: HRSA 25 042 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
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| National Telehealth Resource Center program Apply for HRSA 25 043 Funding Number: HRSA 25 043 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
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