Opportunity Information: Apply for CDC RFA DP19 1907
The Mississippi Delta Health Collaborative (MDHC) grant opportunity (CDC RFA DP19-1907) is a CDC-funded cooperative agreement designed to reduce high blood pressure and the related burden of heart disease and stroke across the 18-county Mississippi Delta region. The program is built around the reality that this largely rural, underserved area carries a high burden of hypertension and faces persistent inequities tied to race/ethnicity, income, and access to timely, high-quality care. The central aim is not only to improve blood pressure prevention and control for the general adult population, but also to narrow the gaps experienced by priority groups of adults with uncontrolled hypertension who are disproportionately affected by barriers like limited healthcare access, inconsistent follow-up, and variable quality of care.
At its core, the opportunity supports population-wide and priority-population approaches that strengthen how communities and healthcare systems prevent, identify, and manage hypertension. The CDC expects the funded applicant to implement or enhance proven strategies that work at scale, with a strong emphasis on health systems interventions and community-clinical linkages. In practical terms, this means improving how clinics and health systems find and accurately diagnose patients with high blood pressure, treat them consistently using evidence-based clinical practices, support medication adherence and self-measured blood pressure monitoring, and connect patients to community resources that help address social and practical barriers. The approach is meant to function across the entire 18-county region rather than in isolated pockets, while still concentrating effort where the burden and disparities are greatest.
A key feature of the NOFO is flexibility through a menu of strategies. Rather than prescribing a single rigid model, the applicant selects specific evidence-based strategies that match local capacity, experience, and the best opportunities for reach and measurable impact. Importantly, the selected strategies are expected to be applied in the same high-burden communities so the work reinforces itself. For example, improvements in clinical hypertension control can be strengthened by community supports like referral pathways, blood pressure screening and follow-up supports, patient navigation, and other linkage mechanisms that help people move smoothly between the community and clinical settings. This is intended to create a coordinated, layered intervention rather than disconnected activities.
In addition to the core evidence-based work, the NOFO also encourages a smaller set of innovative strategies to reduce risks, complications, or barriers to preventing heart disease and stroke among high-burden populations in a subset of communities. These innovations are meant to complement the core strategies and address stubborn obstacles that traditional approaches may not fully solve, such as practical access barriers, challenges in sustained engagement, or gaps in continuity of care. Just as with the core strategies, the innovative components must be implemented and evaluated, signaling that the CDC is looking for both action and credible evidence about what worked, for whom, and under what conditions.
From an administrative standpoint, this is a discretionary cooperative agreement, which typically implies substantial federal involvement beyond a standard grant, often including collaboration, technical assistance, and alignment with CDC priorities and performance expectations. The funding opportunity was issued by the Department of Health and Human Services, Centers for Disease Control and Prevention (NCCDPHP), under CFDA 93.816. The award ceiling listed is $3,150,000, with one expected award, indicating a single applicant would be responsible for coordinating the regional effort at a scale large enough to cover the full Mississippi Delta footprint. The original posting dates show a creation date of May 16, 2019, with an original closing date of July 16, 2019 (applications due by 11:59 p.m. ET). Eligibility is labeled broadly as "Others" with additional eligibility details referenced in the full announcement, suggesting the CDC anticipated a specific type of capable lead organization (or a lead with strong partners) able to manage regional partnerships, implementation, and evaluation.
Overall, MDHC is structured as a regional, equity-focused hypertension and cardiovascular risk reduction initiative. It prioritizes building durable systems across clinics and communities, using evidence-based methods for blood pressure control while also testing targeted innovations to tackle persistent barriers. The expected result is improved hypertension prevention and control, fewer heart disease and stroke complications over time, and measurable progress in reducing disparities among the Mississippi Delta populations carrying the heaviest burden.Apply for CDC RFA DP19 1907
- The Department of Health and Human Services, Centers for Disease Control - NCCDPHP in the health sector is offering a public funding opportunity titled "Mississippi Delta Health Collaborative (MDHC)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.816.
- This funding opportunity was created on May 16, 2019.
- Applicants must submit their applications by Jul 16, 2019 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $3,150,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Mississippi Delta Health Collaborative (MDHC) Grant (CDC RFA DP19-1907) - FAQs
1) What is the Mississippi Delta Health Collaborative (MDHC) grant opportunity?
The MDHC grant opportunity (CDC RFA DP19-1907) is a CDC-funded cooperative agreement designed to reduce high blood pressure and the related burden of heart disease and stroke across the 18-county Mississippi Delta region.
2) What is the main goal of this cooperative agreement?
The central aim is to improve blood pressure prevention and control for the general adult population and to narrow gaps for priority groups of adults with uncontrolled hypertension who experience disproportionate barriers to care.
3) What geographic area does the program cover?
The opportunity focuses on the full 18-county Mississippi Delta region, with an expectation that the work functions across the entire region rather than in isolated pockets.
4) Why is the Mississippi Delta region a focus of this funding?
The region is largely rural and underserved, has a high burden of hypertension, and faces persistent inequities tied to race/ethnicity, income, and access to timely, high-quality care.
5) Who is the program intended to help?
The program targets the general adult population while placing added emphasis on priority groups of adults with uncontrolled hypertension who are disproportionately affected by barriers such as limited healthcare access, inconsistent follow-up, and variable quality of care.
6) What types of strategies does CDC expect the funded applicant to use?
CDC expects implementation or enhancement of proven, evidence-based strategies that work at scale. The approach emphasizes health systems interventions and community-clinical linkages to strengthen prevention, identification, and management of hypertension.
7) What are examples of health systems interventions mentioned in the opportunity?
Examples include improving how clinics and health systems find and accurately diagnose people with high blood pressure, treat patients consistently using evidence-based clinical practices, support medication adherence and self-measured blood pressure monitoring, and improve follow-up.
8) What are community-clinical linkages in the context of this program?
Community-clinical linkages refer to referral pathways and connection mechanisms that help people move smoothly between community settings and clinical care, including connections to community resources that address social and practical barriers.
9) Does the NOFO require a single specific model, or can applicants choose strategies?
The NOFO includes flexibility through a menu of strategies. Rather than requiring one rigid model, the applicant selects specific evidence-based strategies that align with local capacity, experience, and opportunities for reach and measurable impact.
10) Is there an expectation that selected strategies will be coordinated rather than separate efforts?
Yes. The selected strategies are expected to be applied in the same high-burden communities so that the work reinforces itself, creating a coordinated, layered intervention rather than disconnected activities.
11) How does the opportunity address health equity and disparities?
The opportunity is explicitly equity-focused. It aims not only to improve overall hypertension prevention and control, but also to reduce disparities linked to race/ethnicity, income, and access to quality care among high-burden populations.
12) Are innovative strategies allowed, or is the focus only on established evidence-based approaches?
In addition to core evidence-based strategies, the NOFO encourages a smaller set of innovative strategies in a subset of communities to reduce risks, complications, or barriers among high-burden populations.
13) What is the purpose of the innovative strategies component?
The innovative strategies are meant to complement the core work and tackle stubborn obstacles that traditional approaches may not fully solve, such as practical access barriers, sustained engagement challenges, or gaps in continuity of care.
14) Do the innovative strategies need to be evaluated?
Yes. The innovative components must be implemented and evaluated, reflecting an expectation for both action and credible evidence about what worked, for whom, and under what conditions.
15) What type of award mechanism is this?
This is a discretionary cooperative agreement. This typically implies substantial federal involvement beyond a standard grant, often including collaboration, technical assistance, and alignment with CDC priorities and performance expectations.
16) Which federal agency issued this funding opportunity?
The funding opportunity was issued by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), NCCDPHP.
17) What is the CFDA number associated with this opportunity?
The opportunity is listed under CFDA 93.816.
18) How much funding is available?
The award ceiling listed is $3,150,000.
19) How many awards does CDC expect to make?
The notice indicates one expected award, meaning a single applicant would be responsible for coordinating a regional effort at the scale needed to cover the full Mississippi Delta footprint.
20) What are the important dates for this opportunity?
The opportunity shows a creation date of May 16, 2019, and an original closing date of July 16, 2019. Applications were due by 11:59 p.m. ET on the closing date.
21) Who is eligible to apply based on the information provided?
Eligibility is labeled broadly as "Others," with additional eligibility details referenced in the full announcement. The description suggests CDC anticipated a capable lead organization (or a lead with strong partners) able to manage regional partnerships, implementation, and evaluation.
22) What is the expected role of the funded applicant across the region?
The funded applicant is expected to coordinate the regional effort, implement or enhance evidence-based strategies at scale, strengthen clinical and community connections, and ensure the approach reaches across the 18-county region while concentrating effort where burden and disparities are greatest.
23) What kinds of outcomes is this initiative aiming to achieve?
The expected results include improved hypertension prevention and control, fewer heart disease and stroke complications over time, and measurable progress in reducing disparities among the Mississippi Delta populations carrying the heaviest burden.
24) Is the program focused only on clinical care?
No. While there is a strong emphasis on health systems interventions, the program also supports community approaches and community-clinical linkages to address barriers and support people outside of traditional clinical settings.
25) How does the program intend to support people with hypertension beyond diagnosis and prescribing?
The approach described includes supports such as medication adherence assistance, self-measured blood pressure monitoring, consistent evidence-based treatment practices, improved follow-up, and connections to community resources that help address social and practical barriers.
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