Opportunity Information: Apply for PAR 17 464
The National Institutes of Health (NIH) funding opportunity PAR-17-464, titled "Research to Improve Native American Health (R21 Clinical Trial Optional)," supports exploratory and developmental projects aimed at improving health outcomes for Native American populations. For this announcement, "Native Americans" is defined broadly to include Alaska Native, American Indian, and Native Hawaiian communities, with "Native Hawaiian" specifically referring to individuals whose ancestors were native to the Hawaiian Islands prior to 1778. The overall emphasis is on early-stage, hypothesis-generating, or proof-of-concept work that can build a foundation for larger studies and practical interventions that fit the cultural and community contexts of the populations being served.
The FOA is designed for R21-style research, which typically funds smaller, shorter-term projects that test new ideas, establish feasibility, or refine research tools and approaches. The announcement encourages several types of work: secondary analyses of existing datasets (including data collected by Tribal Epidemiology Centers), merging or linking multiple data sources to answer high-priority health questions, pilot and feasibility studies that help determine whether a larger effort is workable, and the assessment or validation of measures that are being created or adapted for Native American communities. The "clinical trial optional" language signals that applicants may propose a clinical trial if it fits the project goals, but a clinical trial is not required.
Projects are expected to be culturally appropriate and tied to real-world improvements in health and quality of life. Priority areas described in the announcement include research that promotes healthy lifestyles; improves health behaviors and social conditions; and/or strengthens environmental conditions connected to chronic disease prevention and management. It also highlights prevention or reduction of tobacco, alcohol, and other drug use; improvements in mental health outcomes; reduced risk of HIV infection; better treatment adherence; and enhancements to health-care delivery and systems so that standards of care are adopted and quality of life improves. In practice, this means proposals should not only address important health problems but also demonstrate an understanding of community context, relevance, and the pathways by which the research could translate into meaningful change.
Eligibility is broad and includes many domestic organization types that commonly apply to NIH grants. Eligible applicants listed include state, county, and city governments; special district governments; independent school districts; public and state-controlled colleges and universities; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofits (both 501(c)(3) and non-501(c)(3)); for-profit organizations (other than small businesses); small businesses; and other entities. The FOA also calls out additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. While foreign institutions are not eligible to apply, the FOA allows foreign components only in a narrow circumstance: when the ancestral catchment areas of tribes cross U.S. national boundaries, consistent with NIH policy definitions.
From a funding details standpoint, this is a discretionary grant opportunity under NIH with activity categories spanning education, environment, and health, and it is associated with multiple CFDA numbers (93.113, 93.242, 93.273, 93.279, 93.307, and 93.393). The listed award ceiling is $200,000. The opportunity was originally created on September 29, 2017, and the provided original closing date is August 14, 2020. Overall, the announcement is structured to help researchers and community-serving organizations test promising approaches, make better use of existing data resources, and develop culturally grounded evidence that can be scaled into stronger interventions and healthier systems for Native American communities.Apply for PAR 17 464
- The National Institutes of Health in the education, environment, health sector is offering a public funding opportunity titled "Research to Improve Native American Health (R21 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.242, 93.273, 93.279, 93.307, 93.393.
- This funding opportunity was created on 2017-09-29.
- Applicants must submit their applications by 2020-08-14. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: NIH PAR-17-464 - Research to Improve Native American Health (R21 Clinical Trial Optional)
What is PAR-17-464?
PAR-17-464 is a National Institutes of Health (NIH) funding opportunity titled "Research to Improve Native American Health (R21 Clinical Trial Optional)." It supports exploratory and developmental research projects intended to improve health outcomes for Native American populations.
What is the main purpose of this funding opportunity?
The main purpose is to fund early-stage, hypothesis-generating, or proof-of-concept research that can lay the groundwork for larger studies and practical interventions that fit the cultural and community contexts of the populations being served.
What does "R21" mean in this announcement?
This opportunity uses the NIH R21 mechanism, which is typically used to support smaller, shorter-term projects designed to test new ideas, establish feasibility, refine research tools, or generate preliminary data that can support future, larger research efforts.
What does "Clinical Trial Optional" mean?
"Clinical Trial Optional" means an applicant may propose a clinical trial if it aligns with the project goals, but a clinical trial is not required for the application.
Who is included under the term "Native Americans" for this FOA?
For this announcement, "Native Americans" is defined broadly to include Alaska Native, American Indian, and Native Hawaiian communities.
How does the FOA define "Native Hawaiian"?
"Native Hawaiian" refers to individuals whose ancestors were native to the Hawaiian Islands prior to 1778.
What kinds of projects does the FOA encourage?
The FOA encourages exploratory and developmental work such as secondary analyses of existing datasets, linking or merging multiple data sources, pilot and feasibility studies, and assessment or validation of measures that are created or adapted for Native American communities.
Are secondary analyses of existing datasets allowed?
Yes. The announcement specifically encourages secondary analyses of existing datasets, including data collected by Tribal Epidemiology Centers.
Can applicants merge or link multiple datasets under this FOA?
Yes. The FOA encourages merging or linking multiple data sources to address high-priority health questions relevant to Native American populations.
Are pilot and feasibility studies appropriate for this opportunity?
Yes. Pilot and feasibility studies are explicitly encouraged, particularly when they help determine whether a larger study or intervention is workable in the intended community context.
Does the FOA support developing or validating research measures for Native American communities?
Yes. The FOA encourages assessment or validation of measures that are being created or adapted specifically for Native American communities.
What general topic areas does the FOA prioritize?
Priority areas include research that promotes healthy lifestyles; improves health behaviors and social conditions; and/or strengthens environmental conditions connected to chronic disease prevention and management.
Does the FOA include substance use as a priority area?
Yes. The announcement highlights prevention or reduction of tobacco, alcohol, and other drug use as areas of interest.
Does the FOA include mental health research?
Yes. Improvements in mental health outcomes are specifically highlighted as a priority area.
Does the FOA include HIV-related research?
Yes. The FOA highlights research aimed at reducing risk of HIV infection.
Is treatment adherence research relevant to this opportunity?
Yes. The FOA identifies better treatment adherence as an area of interest.
Does the FOA support health-care delivery and systems research?
Yes. Enhancements to health-care delivery and systems are included, with an emphasis on adopting standards of care and improving quality of life.
Are projects expected to be culturally appropriate?
Yes. Projects are expected to be culturally appropriate and connected to real-world improvements in health and quality of life for the communities being served.
What does the FOA mean by emphasizing community context and relevance?
Based on the description, proposals should show an understanding of the community context, explain why the research is relevant, and describe how the work could translate into meaningful change in health outcomes or systems of care.
What types of organizations are eligible to apply?
Eligibility is broad and includes many U.S.-based organization types commonly eligible for NIH grants, including various government entities, educational institutions, tribal entities, nonprofits, and businesses.
Are state, county, or city governments eligible?
Yes. State, county, and city (or township) governments are listed as eligible applicants.
Are special district governments eligible?
Yes. Special district governments are listed as eligible applicants.
Are independent school districts eligible?
Yes. Independent school districts are listed as eligible applicants.
Are public colleges and universities eligible?
Yes. Public and state-controlled institutions of higher education are listed as eligible applicants.
Are private universities or colleges eligible?
Yes. Private institutions of higher education are listed as eligible applicants.
Are federally recognized tribal governments eligible?
Yes. Federally recognized Native American tribal governments are listed as eligible applicants.
Are tribal organizations that are not federally recognized eligible?
Yes. Tribal organizations (other than federally recognized tribal governments) are listed as eligible applicants.
Are public housing authorities or Indian housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are listed as eligible applicants.
Are nonprofit organizations eligible?
Yes. Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status are listed as eligible applicants.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are listed as eligible applicants, and small businesses are also listed separately as eligible.
Are Alaska Native and Native Hawaiian Serving Institutions eligible?
Yes. Alaska Native and Native Hawaiian Serving Institutions are specifically called out as eligible applicant categories.
Are AANAPISI institutions eligible?
Yes. Asian American Native American Pacific Islander Serving Institutions (AANAPISI) are listed as eligible.
Are Hispanic-serving institutions eligible?
Yes. Hispanic-serving institutions are listed as eligible.
Are Historically Black Colleges and Universities (HBCUs) eligible?
Yes. HBCUs are listed among eligible applicant categories.
Are Tribally Controlled Colleges and Universities (TCCUs) eligible?
Yes. TCCUs are listed among eligible applicant categories.
Are faith-based or community-based organizations eligible?
Yes. Faith-based and community-based organizations are specifically mentioned as eligible.
Are regional organizations eligible?
Yes. Regional organizations are listed as eligible applicant categories.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are listed as eligible.
Are federal agencies eligible to apply?
Yes. Eligible federal agencies are listed as eligible applicants.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply under this FOA.
Are foreign components allowed in any circumstances?
Yes, but only in a narrow circumstance: when the ancestral catchment areas of tribes cross U.S. national boundaries, consistent with NIH policy definitions.
What is the award ceiling listed for this opportunity?
The listed award ceiling is $200,000.
What type of grant is this described as?
This is described as a discretionary grant opportunity under NIH.
What activity categories are associated with this opportunity?
The opportunity is associated with activity categories spanning education, environment, and health.
Which CFDA numbers are associated with this FOA?
The FOA is associated with multiple CFDA numbers: 93.113, 93.242, 93.273, 93.279, 93.307, and 93.393.
When was this opportunity originally created?
The opportunity was originally created on September 29, 2017.
What is the original closing date provided for this opportunity?
The provided original closing date is August 14, 2020.
What kind of impact is NIH looking for from funded projects?
Based on the FOA description, NIH is looking for research that can build evidence and practical foundations for interventions and improved systems of care that are culturally grounded and can translate into meaningful improvements in health and quality of life for Native American communities.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 17 464) also looked into and applied for these:
| Funding Opportunity |
|---|
| Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) Apply for PAR 17 496 Funding Number: PAR 17 496 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R01 Clinical Trial Optional) Apply for PA 18 284 Funding Number: PA 18 284 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Addressing Health Disparities through Effective Interventions Among Immigrant Populations (R21 Clinical Trial Optional) Apply for PA 18 285 Funding Number: PA 18 285 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| NIH Research Project Grant (Parent R01 Clinical Trial Required) Apply for PA 18 345 Funding Number: PA 18 345 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Research to Action: Assessing and Addressing Community Exposures to Environmental Contaminants (R01 Clinical Trial Optional) Apply for PA 18 260 Funding Number: PA 18 260 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Required) Apply for PA 18 344 Funding Number: PA 18 344 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Environmental Exposures and Health: Exploration of Non-Traditional Settings (R21 Clinical Trial Optional) Apply for PA 18 160 Funding Number: PA 18 160 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Environmental Exposures and Health: Exploration of Non-Traditional Settings (R01 Clinical Trial Optional) Apply for PA 18 142 Funding Number: PA 18 142 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Independent Scientist Award (Parent K02 - Independent Clinical Trials Not Allowed) Apply for PA 18 371 Funding Number: PA 18 371 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Midcareer Investigator Award in Patient-Oriented Research (Parent K24 - No Independent Clinical Trials) Apply for PA 18 394 Funding Number: PA 18 394 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| NIH Exploratory/Developmental Research Grant Program ( Parent R21 Clinical Trial Not Allowed) Apply for PA 18 489 Funding Number: PA 18 489 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33) Apply for PA 18 672 Funding Number: PA 18 672 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Innovative Basic Research on Adducts in Cancer Risk Identification and Prevention (R01 Clinical Trial Not Allowed) Apply for PAR 18 704 Funding Number: PAR 18 704 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Innovative Basic Research on Adducts in Cancer Risk Identification and Prevention (R21 Clinical Trial Not Allowed) Apply for PAR 18 703 Funding Number: PAR 18 703 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $200,000 |
| Electronic Nicotine Delivery Systems (ENDS): Basic Mechanisms of Health Effects (R01 - Clinical Trial Not Allowed) Apply for PAR 18 845 Funding Number: PAR 18 845 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Electronic Nicotine Delivery Systems (ENDS): Basic Mechanisms of Health Effects (R21 - Clinical Trial Not Allowed) Apply for PAR 18 846 Funding Number: PAR 18 846 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional) Apply for RFA ES 18 002 Funding Number: RFA ES 18 002 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $1,750,000 |
| Emerging Global Leader Award (K43 Independent Clinical Trial Required) Apply for PAR 19 038 Funding Number: PAR 19 038 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
| Countermeasures Against Chemical Threats (CounterACT): Identification of Therapeutic Lead Compounds (U01 Clinical Trial Not Allowed) Apply for PAR 19 039 Funding Number: PAR 19 039 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: $300,000 |
| Countermeasures Against Chemical Threats (CounterACT): Optimization of Therapeutic Lead Compounds (U01 Clinical Trial Optional) Apply for PAR 19 040 Funding Number: PAR 19 040 Agency: National Institutes of Health Category: Education, Environment, Health Funding Amount: Case Dependent |
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