Opportunity Information: Apply for PAR 21 143
The NHGRI Predoctoral to Postdoctoral Transition Award for a Diverse Genomics Workforce (F99/K00), listed as PAR-21-143, is a National Institutes of Health (NIH) grant program created by the National Human Genome Research Institute (NHGRI) to help talented doctoral students from diverse backgrounds move smoothly from late-stage PhD training into a high-quality postdoctoral position in genomics. The central idea is to fund a clearly structured, two-step training and career development pathway that supports both the final push to complete the dissertation and the critical transition into postdoctoral research, with the long-term goal of building a more diverse and inclusive pipeline of independent genomics researchers. NHGRI explicitly highlights inclusion of individuals from groups underrepresented in biomedical, clinical, behavioral, and social sciences, and the program is designed to provide not only research support but also deliberate career development so recipients are better positioned to compete for later-stage independent funding.
The award has two connected phases. The F99 phase supports the trainee while they finish their doctoral dissertation work, helping them reach key milestones needed for the PhD and strengthening their preparation for the next career stage. After successful completion of the F99 phase and the PhD, the award transitions to the K00 phase, which supports the recipient in a strong postdoctoral research environment. The postdoctoral work is expected to be firmly centered in genomics and can span a broad range of focus areas, including scientific and medical genomics as well as ethical, social, and legal dimensions of genomics research. In other words, the program is not limited to bench science; it also recognizes the importance of policy, ethics, and societal impacts as core parts of the genomics ecosystem.
A key compliance point in the announcement is its stance on clinical trials. Applicants are not allowed to propose leading an independent clinical trial under this FOA. However, they can propose gaining research experience within a clinical trial as long as that trial is led by a sponsor or co-sponsor. This distinction matters for trainees whose genomics interests involve clinical research: the mechanism supports hands-on clinical trial experience and professional development, but not the responsibility of being the primary driver of an independent trial.
Eligibility is broad at the organizational level, consistent with many NIH funding opportunities, and includes a wide array of U.S.-based entities such as public and private institutions of higher education, state and local governments, certain tribal governments and tribal organizations, nonprofits (with or without 501(c)(3) status), and for-profit organizations (including small businesses). The announcement also calls out additional eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. At the same time, the FOA makes clear limits related to foreign participation: non-U.S. entities (foreign organizations and foreign institutions) are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible to apply. That said, “foreign components” as defined under the NIH Grants Policy Statement are allowed, meaning a U.S.-based applicant organization may, under NIH rules, include certain justified foreign elements of the project even though a foreign institution cannot be the applicant.
From a practical standpoint, this opportunity is best understood as a structured career bridge: it supports finishing the PhD, then launching into a mentored postdoc with genomics-focused research and career development, all with the intention of producing trainees who are positioned to become independent investigators. The program sits within NIH’s health funding area (CFDA 93.172), uses the grant funding instrument, and was created on March 25, 2021, with an original closing date listed as December 3, 2024. The announcement text does not specify an award ceiling or the expected number of awards in the provided details, so applicants typically need to consult the full FOA and NIH guidance for budget structure, allowable costs, and the current submission schedule.Apply for PAR 21 143
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NHGRI Predoctoral to Postdoctoral Transition Award for a Diverse Genomics Workforce (F99/K00)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172.
- This funding opportunity was created on 2021-03-25.
- Applicants must submit their applications by 2024-12-03. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: NHGRI Predoctoral to Postdoctoral Transition Award for a Diverse Genomics Workforce (F99/K00) (PAR-21-143)
What is the NHGRI F99/K00 (PAR-21-143) program?
The NHGRI Predoctoral to Postdoctoral Transition Award for a Diverse Genomics Workforce (F99/K00), PAR-21-143, is an NIH grant program from the National Human Genome Research Institute (NHGRI). It is designed to help talented doctoral students from diverse backgrounds transition smoothly from late-stage PhD training into a strong, genomics-focused postdoctoral position, with the long-term aim of strengthening and diversifying the pipeline of independent genomics researchers.
What is the main purpose of this award?
The purpose is to fund a clearly structured, two-step training and career development pathway: (1) support for completing the dissertation (F99 phase) and (2) support for mentored postdoctoral research and career development in genomics (K00 phase). The program emphasizes both research progress and deliberate career development so recipients are better positioned to compete for later independent funding.
Who is this opportunity intended to support?
It is intended to support late-stage doctoral students, particularly individuals from groups underrepresented in biomedical, clinical, behavioral, and social sciences, who are preparing to finish a PhD and then move into a high-quality postdoctoral position in genomics.
How is the award structured?
The award has two connected phases. The F99 phase supports the trainee during the final push to complete the PhD dissertation work. After successful completion of the F99 phase and the PhD, the award transitions to the K00 phase, which supports the recipient during a mentored postdoctoral appointment in a strong genomics research environment.
What does the F99 phase support?
The F99 phase supports the trainee while they finish their doctoral dissertation work. It is meant to help the trainee reach key milestones needed for the PhD and strengthen preparation for the next career stage.
What does the K00 phase support?
The K00 phase supports the recipient in a postdoctoral research environment after the PhD is completed. The postdoctoral work is expected to be firmly centered in genomics and paired with structured career development.
Does the postdoctoral research have to be in genomics?
Yes. The postdoctoral work supported in the K00 phase is expected to be firmly centered in genomics.
Is this award limited to bench science genomics?
No. The program recognizes a broad range of genomics-related research areas, including scientific and medical genomics as well as ethical, social, and legal dimensions of genomics research.
Can applicants propose research focused on ethical, social, or legal issues in genomics?
Yes. The described scope includes ethical, social, and legal dimensions of genomics research, reflecting the program’s view that these areas are part of the broader genomics ecosystem.
Are independent clinical trials allowed under this FOA?
No. Applicants are not allowed to propose leading an independent clinical trial under this funding opportunity announcement.
Can a trainee gain clinical trial experience under this program?
Yes. A trainee may propose gaining research experience within a clinical trial, as long as the clinical trial is led by a sponsor or co-sponsor. The key distinction is that the trainee cannot be the lead for an independent clinical trial under this FOA.
What types of organizations are eligible to apply?
Eligible applicant organizations include a wide range of U.S.-based entities, such as public and private institutions of higher education, state and local governments, certain tribal governments and tribal organizations, nonprofits (with or without 501(c)(3) status), and for-profit organizations (including small businesses).
Are minority-serving institutions specifically mentioned as eligible?
Yes. The announcement calls out eligible applicant types that include Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are listed among eligible applicant types in the provided description.
Are for-profit organizations eligible to apply?
Yes. For-profit organizations, including small businesses, are included among eligible applicant organizations.
Are U.S. territories or possessions included as eligible applicants?
Yes. U.S. territories or possessions are included among eligible applicant types in the provided information.
Can foreign organizations apply as the applicant institution?
No. Non-U.S. entities (foreign organizations and foreign institutions) are not eligible to apply as the applicant organization.
Can a non-U.S. component of a U.S. organization apply?
No. Non-U.S. components of U.S. organizations are not eligible to apply under this opportunity.
Are any foreign elements allowed at all?
Yes. “Foreign components,” as defined under the NIH Grants Policy Statement, are allowed. This means a U.S.-based applicant organization may be able to include justified foreign elements of the project under NIH rules, even though a foreign institution cannot be the applicant.
What is the long-term goal of the program?
The long-term goal is to build a more diverse and inclusive pipeline of independent genomics researchers by supporting trainees through dissertation completion and into a strong postdoctoral environment with deliberate career development.
What funding instrument and NIH area does this opportunity fall under?
It uses the grant funding instrument and sits within NIH’s health funding area, listed as CFDA 93.172 in the provided description.
When was this program created and what is the listed closing date?
The program was created on March 25, 2021, and the original closing date listed in the provided information is December 3, 2024.
Does the provided information include an award ceiling or the expected number of awards?
No. The provided details do not specify an award ceiling or the expected number of awards. The description indicates applicants typically need to consult the full FOA and NIH guidance for budget structure, allowable costs, and the current submission schedule.
Where should applicants look for budget rules and the current submission schedule?
The provided description indicates applicants should consult the full FOA and NIH guidance for budget structure, allowable costs, and the current submission schedule, since those details are not included in the summary provided.
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